Doxycycline, also known as Vibramycin, is a type of tetracycline that is better absorbed by the gastrointestinal tract and has a lower risk of nephrotoxicity compared to other tetracyclines. It is commonly used in dermatology and otolaryngology for the treatment of conditions such as acne, respiratory tract infections, soft tissue infections, digestive tract infections, genitourinary system infections, periodontitis, malaria, typhus, and more.
Antibiotics are often considered lifesaving, and they have indeed helped to combat infections and contain epidemics since their invention. However, their negative impact on the human body, particularly the gastrointestinal flora, is well known. Antibiotics can kill the beneficial bacteria in the gut, leading to serious health disorders. That is why a supportive therapy is always prescribed alongside antibiotic therapy.
Pharmaceutical companies have conducted extensive research to minimize the negative impact of antibiotics on human health and to develop new generation drugs that are less harmful and more effective. Vibramycin is one such medication and belongs to the new generation of antibiotics that have a milder impact on health and a higher therapeutic efficacy.
Meal does not influence the level of the drug absorption. The medication is absorbed in the gastrointestinal tract quickly and effectively. Inside the human body Vibramycin is effectively distributed between tissues and internal organs; the accumulation of therapeutic quantities takes place in 30-45 minutes after the intake. The preparation penetrates in the cerebrospinal fluid, placenta and breast milk. It is removed from the body with urine and stool.
Uses
Vibramycin is characterized by the wide spectrum of therapeutic uses.
It is used for the treatment of inflectional diseases caused by the susceptible organisms:
- Respiratory infections: acute and chronic bronchitis, pharyngitis, trachitis, bronchial pneumonia, lobar pneumonia, lung abscess;
- ENT infections: otitis, tonsillitis, sinusitis and other;
- Genitourinary infections: cystitis, pyelonephritis, prostatitis, urethritis, urethrocystitis, genitourinary mycoplasmosis, endometritis, endocervicitis, orchiepididymitis, gonorrhea;
- Gastrointestinal infections: cholecystitis, cholangitis, gastroenterocolitis, bacillary dysentery, ‘traveler’s’ dysentery;
- Skin infections: abscesses, phlegmons, furunculosis, panaris, infected burns, wounds etc.
The other inflectional diseases which are treated with the help of Vibramycin include eye diseases, syphilis, chlamydia, legionellosis, frambesia, rickettsia diseases, different types of fever and typhoid, Lyme disease, cholera, malaria, brucellosis, osteomyelitis, endocarditis, peritonitis and so on.
Vibramycin is also widely used for the prevention of post-surgery complications, malaria caused by Plasmodium falciparum if the patient travels around the area of the location of strains resistant to chloroquine and pyremathamine.
How to buy Doxycycline Online
Vibramycin can be purchased both in physical drug stores and online through pharmaceutical websites. While purchasing from a traditional drug store is a well-established method, online shopping for pharmaceutical products is becoming increasingly popular due to its numerous benefits. You can easily order Doxycycline in the desired dosage and form by visiting a Canadian Pharmacy website, selecting the product, and placing an order. Delivery time will vary depending on your location, but it can range from several hours to several days.
In addition to ordering medications, you can also take advantage of other services offered by Canadian pharmacies. If you are unfamiliar with Doxycycline, you can find information on the website or seek guidance from the customer support team. Our experts will provide comprehensive answers to any questions you may have about the product and the status of your order.
The pharmaceutical market offers both original Vibramycin in two forms and dosages, as well as generic versions of the medication. The good news is that generic Vibramycin has been approved by the FDA with an “AB” rating, meaning that it is equivalent to the original product and safe to use. Additionally, generic versions are often more affordable than the branded product.
Doxycycline 100mg from Immune Pharma is available in capsules of 50 mg and 100 mg, while generic Vibramycin is also offered in a 25 mg powder form for oral suspension. The generic versions of Vibramycin are manufactured by pharmaceutical companies in the USA and Israel.
It is important to note that, even though generic versions have an AB rating, they must contain the same active ingredient, but may contain different auxiliary substances that could cause allergic reactions. Therefore, patients should carefully review the pharmaceutical content, even of the safest generic versions, to avoid negative consequences.
Content
Vibramycin contains Doxycycline as an active ingredient. Doxycycline is a semisynthetic antibiotic aimed at inhibiting the process of protein synthesis in pathogenic germs. Vibramycin also contains auxiliary substances such as Lactose, Magnesium Stearate, cornflour and other.
Vibramycin is available in the form of capsules. Each pack of Vibramycin contains 10 pieces.
The other therapeutic forms of Vibramycin are tablets and Lyophilizate for solution for intravenous injections.
Doses
The dosage of Vibramycin per each intake depends upon the disease and the severity of the case. Average daily dosage for adults is 200 mg at the beginning of the therapy and 100 mg as a supportive dosage in the further course. Every medical case requires its own scheme and duration of treatment.
Capsules are swallowed with much water. The medication is better absorbed if taken on empty stomach. If the patient misses the dose he should take it as soon as possible. However it a lot of time passes since the missed dose it is better to continue treatment according to the schedule. Double dose is not permitted!
Intravenous injections are used when it is necessary to reach large concentration of the medicine in blood or it is difficult for the patient to take the pill orally. Injections are preferable in severe cases of suppurrative – septic diseases. The dosage for injections should not be less than 0.1 mg/ml and more than 1 mg/ml.
Doxycycline and other medications
If Vibramycin is co-administered with antacids or iron-containing drugs as well as Sodium bicarbonate it may decrease their therapeutic effectiveness. Therefore it is necessary to make the 3 hour intervals between the intakes of the given medications.
Vibramycin intensifies the action of some antidiabetic medications and anti-coagulant coumarin derivatives so the decrease of dosages of the given drugs is necessary.
Being co-administered with bacterial antibiotics Vibramycin decreases their effectiveness. The same situation occurs with oral contraceptives so patients should apply different contraceptive methods.
Vibramycin is not recommended to be taken together with Retinol, Methotrexate, and Cyclosporine A.
Simultaneous use of Vibramycin and barbiturates speeds up the metabolism of Doxycycline so the increase of daily dosages of the medication is possible.
Food interactions
Vibramycin is not known to have dangerous interactions with food. Taking the capsule with meal does not influence the therapeutic effect of the medication.
Alcohol is not recommended during the therapy with Vibramycin especially if taken together. Alcohol speeds up the metabolism of Doxycycline thus causing the process of half – removal of the Vibramycin’s active ingredient. As a result, the effectiveness of Vibramycin decreases.
Some experts consider that simultaneous intake of alcohol and antibiotics may cause serious damages to the human liver. There are no proofs of the given situation as far as Vibramycin is concerned. However, doctors strongly recommend that their patients should refrain from drinking alcohol during the therapy period.
Who should not take Vibramycin?
Vibramycin is not used in patients who suffer from the increased sensitivity to any component of the medication.
Kidney and liver failure is also the serious reason for the doctors not to recommend Vibramycin for their patients as liver and kidney take part in the process of the medication removal from the human body and may be seriously damaged in case of any existing problems.
Vibramycin is not prescribed for children under 8 years old as well as pregnant and lactating women as the active ingredient of the drug penetrates both into placenta and breast milk.
The other Vibramycin contraindications include porphyria, leukopenia and systemic lupus erythematosis.
It is important that the patients inform their doctors about the suffered or present diseases in order to avoid unpleasant consequences for their health.
Side effects
Vibramycin therapy mat cause negative consequences most of which are connected with human nervous and gastrointestinal systems as well as various allergic reactions. The most common symptoms of the side effects involve dizziness, loss of appetite, nausea and vomiting, diarrhea, glossitis, stomatitis, gastritis, esophagitis, pseudomembranous colitis and hepatotoxicity.
In some cases long-term or repeated course of treatment may cause the development of super infections due to the generation of bacteria or fungi that are not responsive to Vibramycin.
Skin reactions may include changes in skin colour, skin rash, dermatitis and so on. Allergic reactions include, but are not limited to Urticaria, eosinophilia, short breathing, anaphylaxis, angioneurotic edema and other disturbances.
Adult patients may also suffer from the increased blood pressure, headaches and vision problems.
Vibramycin for cats and dogs
Vibramycin is also widely used in veterinary practice for the treatment of cats and dogs suffering from encephalomeningitis.
Encephalomeningitis, the inflammation of cerebral meninges and brain matter, is characterized by the dysfunction of cerebral cortex, subcortical and vegetative centers.
Disturbances of cerebrum and spine in dogs and cats often occur as a subsequent sickness caused by several bacterial and viral infections. These infections include distemper and feline distemper, Aujeszky’s diseases, canicola fever, circling disease, surgical sepsis, development of spinal inflammation and pneumonias. The diseases may also be caused by closed wounds, blast injury and hypothermia of head.
In general, Vibramycin has similar therapeutic indications and is prescribed for animals suffering from various infections and bacterial diseases Vibramycin is designed to treat.
As far as the dosage is concerned large animals are prescribed 200 mg as a starting dosage and 100 mg as a supportive therapy. The dosages for small animals and pets are determined according to their weight at the rate of 4 mg per 1 kg at the beginning of treatment and 1-2 mg – for further support.
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